List of Publications
Book Chapters
3. Preparation of Metal-Containing Peptide Nucleic Acid Bioconjugates on the Solid Phase
Peptide Nucleic Acids, Methods and Protocols, 2nd Edition ed. (Eds. P.E. Nielsen, D. Appella)
G. Gasser,* Humana Press, 2013, in press.
ISBN: 978-1-62703-552-1
2. Synthesis, Characterization and Evaluation of Radiometal-containing Peptide Nucleic Acids
Peptide Nucleic Acids, Methods and Protocols, 2nd Edition ed. (Eds. P.E. Nielsen, D. Appella)
H. Stephan,* C. Förster and G. Gasser,* Humana Press, 2013, in press.
ISBN: 978-1-62703-552-1
1. Metal Compounds as Enzyme Inhibitors
Bioinorganic Medicinal Chemistry (Ed. E. Alessio)
G. Gasser* and N. Metzler-Nolte,* Wiley-VCH, Weinheim, 2011, 351-382.
ISBN: 978-3-527-32631-0
Reviews / Perspectives
5. Organometallic Compounds, an Opportunity for Chemical Biology?
M. Patra and G. Gasser,* ChemBioChem. 2012, 13, 1232 – 1252.
DOI: http://dx.doi.org/10.1002/cbic.201200159
4. The Potential of Organometallic Compounds in Medicinal Chemistry
G. Gasser* and N. Metzler-Nolte,* Curr. Op. Chem. Biol. 2012, 16, 84-91.
DOI: http://dx.doi.org/10.1016/j.cbpa.2012.01.013
3. Small Organometallic Compounds as Antibacterial Agents
M. Patra, G. Gasser* and N. Metzler-Nolte,* Dalton Trans. 2012, 41, 6350-6358.
2. Metal-Containing Peptide Nucleic Acid Conjugates

G. Gasser,* A.M. Sosniak and N. Metzler-Nolte,* Dalton Trans. 2011, 40, 7061-7076. (selected for the cover picture)

1. Organometallic Anticancer Compounds

G. Gasser,* I. Ott* and N. Metzler-Nolte,* J. Med. Chem. 2011, 54, 3-25.


Patent Applications

2. Synthesis of Amino-substituted Metallocene Compounds

G. Gasser, A. Leonidova, T. Joshi, D. Nipkow, A. Frei, J.-E. Penner, S. Konatschnig and M. Patra

Eur. Pat. Appl. (2013), EP13157319.8.

1. Metal-Containing Platensimycin Analogues

N. Metzler-Nolte, G. Gasser, and M. Patra

Eur. Pat. Appl. (2010), EP2226329.
Journal Articles
39.
An Environmentally Benign and Cost-Effective Synthesis of Aminoferrocene and Aminoruthenocene

A. Leonidova, T. Joshi, D. Nipkow, A. Frei, J.-E. Penner, S. Konatschnig, M. Patra and G. Gasser,* Organometallics. 2013, 32, 2037-2040.

38.
Di-Heterometalation of Thiol-Functionalized Peptide Nucleic Acids

T. Joshi, M. Patra, L. Spiccia, and G. Gasser,* Artifical DNA: PNA & XNA, 2013, 4, 11-18. (invited contribution).


37.
 Synthesis of Stable Peptide Nucleic Acid-Modified Gold Nanoparticles and their Assembly onto Gold Surfaces

P. Anstaett, Y. Zheng, T. Thai, A.M. Funston, U. Bach* and G. Gasser,* Angew. Chem. Int. Ed. 2013, 52, 4217–4220.


36.
Novel Water-Soluble 99mTc(I)/Re(I)-Porphyrin Conjugates as Potential Multimodal Agents for Molecular Imaging

C. Spagnul, R. Alberto,* G. Gasser, S. Ferrari, V. Pierroz, A. Bergamo, T. Gianferrara* and E. Alessio, J. Inorg. Biochem, 2013, 122, 57-65.


35.
(η6-Praziquantel)Cr(CO)3 Derivatives with Remarkable In Vitro Anti-schistosomal Activity

M. Patra, K. Ingram, V. Pierroz, S. Ferrari, B. Spingler, R.B. Gasser, J. Keiser* and G. Gasser,* Chem. Eur. J., 2013, 19, 2232-2235.


34.
 Molecular and Cellular Characterization of the Biological Effects of Ruthenium(II) Complexes Incorporating 2-Pyridyl-2-Pyrimidine-4-Carboxylic Acid

V. Pierroz, T. Joshi, A. Leonidova, C. Mari, J. Schür, I. Ott, L. Spiccia,* S. Ferrari,* and G. Gasser,* J. Am. Chem. Soc. 2012, 134, 20376-20387. Highlighted in Chimia and Chemistry in Australia.



33.
 Ferrocenyl Derivatives of the Anthelminc Praziquantel: Design, Synthesis and Biological Evaluation

M. Patra, K. Ingram, V. Pierroz, S. Ferrari, B. Spingler, J. Keiser and G. Gasser,* J. Med. Chem., 2012, 55, 8790-8798.

DOI:  http://dx.doi.org/10.1021/jm301077m

32.
 Electrochemical, Spectroscopic, Magnetic and Structural Studies of Complexes bearing Ferrocenyl Ligands of N-(3-hydroxypicolinoyl)picolinamide

G. Gasser,* C. Mari, M. Burkhart, S.J. Green,* J. Ribas, H. Stoeckli-Evans* and J.H.R. Tucker,* New. J. Chem., 2012, 36, 1819-1827.



31.
 Specific Uptake and Interactions of Peptide Nucleic Acid Derivatives with Biomimetic Membranes

T. Joshi, G. Gasser,* L.M. Martin* and L. Spiccia,* RSC Adv., 2012, 2, 4703-4712.



30.
 Electrochemiluminescent Monomers for Solid Support Synthesis of Ru(II)-PNA Bioconjugates - Multimodal Biosensing Tools with Enhanced Duplex Stability

T. Joshi, G.J. Barbante, P.S. Francis, C.F. Hogan, A.M. Bond, G. Gasser* and L. Spiccia,* Inorg. Chem., 2012, 51, 3302-3315.


29.
 Synthesis, Characterisation and Bioimaging of a New Fluorescent Rhenium-Containing PNA Bioconjugate

G. Gasser,* A. Pinto, S. Neumann, A.M. Sosniak, M. Seitz, K. Merz, R. Heumann and N. Metzler-Nolte,* Dalton Trans., 2012, 41, 2304-2313.



28.
 Sandwich and Half-Sandwich Derivatives of Platensimycin: Synthesis and Biological Evaluation

M. Patra, G. Gasser, M. Wenzel, K. Merz, J.E. Bandow and N. Metzler-Nolte,* Organometallics, 2012, 31, 5760–5771.


27.
 Preparation and Biological Evaluation of Di-Hetero-Organometallic-Containing PNA Bioconjugates

G. Gasser,* S. Neumann, I. Ott, M. Seitz, R. Heumann and N. Metzler-Nolte,* Eur. J. Inorg. Chem., 2011, 5471-5478.


26.
 Synthesis of Optically Active Ferrocene-Containing Platensimycin Derivatives with a C6-C7 Substitution Pattern

M. Patra, G. Gasser, M. Wenzel, K. Merz, J.E. Bandow N. Metzler-Nolte,* Eur. J. Inorg. Chem., 2011, 3295-3302.


25.
 Towards the Preparation of novel Re/99mTc Tricarbonyl-Containing Peptide Nucleic Acid Bioconjugates

G. Gasser,* A.M. Sosniak, A. Leonidova, H. Braband and N. Metzler-Nolte,* Aust. J. Chem., 2011, 64, 1-8 (invited contribution).


24.
 Synthesis and Biological Evaluation of Ferrocene-containing Bioorganometallics Inspired by the Antibiotic Platensimycin Lead Structure

M. Patra, G. Gasser, M. Wenzel, K. Merz, J.E. Bandow and N. Metzler-Nolte,* Organometallics, 2010, 29, 4312-4319.


23.
 Preparation, 99mTc-Labeling and Biodistribution Studies of a PNA Oligomer Containing a New Ligand Derivative of 2,2’-Dipicolylamine

G. Gasser,* K. Jäger, M. Zenker, R. Bergmann, J. Steinbach, H. Stephan* and N. Metzler-Nolte,* J. Inorg. Biochem. 2010, 104, 1133-1140.


22.
Sequential Insertion of three Different Organometallics into a Versatile Building Block Containing a PNA Backbone

M. Patra, G. Gasser,* D. Bobukhov, K. Merz, A.V. Shtemenko and N. Metzler-Nolte,* Dalton Trans. 2010, 39, 5617-5619.
DOI: http://dx.doi.org/10.1039/c003589J

21.
Synthesis and Complexation Properties of Novel Triazoyl-Based Ferrocenyl Ligands

G. Gasser,* J.D. Carr, S.J. Coles, S.J. Green, M.B. Hursthouse, S.M. Cafferkey, H. Stoeckli-Evans, and J.H.R. Tucker,* J. Organomet. Chem. 2010, 695, 249-255.


20.
Thermal Melting Studies of Alkyne and Ferrocene-containing PNA Bioconjugates

A. Sosniak, G. Gasser and N. Metzler-Nolte,* Org. Biomol. Chem. 2009, 7, 4992 – 5000.


19.
Synthesis and Biological Evaluation of Chromium Bioorganometallics Based on the Antibiotic Platensimycin Lead Structure

M. Patra, G. Gasser, K. Merz, I. Ott, J.E. Bandow and N. Metzler-Nolte,* ChemMedChem. 2009, 4, 1930-1938.


18.
“Four-Potential” Ferrocene Labelling of PNA Oligomers via Click Chemistry

N. Hüsken, G. Gasser, S.D. Köster and N. Metzler-Nolbe,* Bioconjugate Chem. 2009, 20, 1578–1586.


17.
Synthesis and Characterisation of Hetero-Bimetallic Organometallic Phenylalanine and PNA Monomer Derivatives

G. Gasser, O. Brosch, A. Ewers, T. Weyhermüller and N. Metzler-Nolte,* Dalton Trans. 2009, 4310-4317. Selected as HOT ARTICLE.


16.
Synthesis, Spectroscopic Properties and Electrochemical Oxidation of RuII Complexes Attached to a Peptide Nucleic Acid Monomer Backbone

N. Nickita, G. Gasser, A.M. Bond and L. Spiccia,* Eur. J. Inorg. Chem. 2009, 14, 2179-2186.


15.
Synthesis and Characterisation of Dicobalthexacarbonyl-Alkyne Amino Acid, Peptide and PNA Monomer Derivatives

G. Gasser, M.A. Neukamm, A. Ewers, O. Brosch, T. Weyhermüller and N. Metzler-Nolte,* Inorg. Chem. 2009, 48, 3157-3166.

DOI: http://dx.doi.org/10.1021/ic900013r

14.
Binding of HIV-1TAR mRNA to a Peptide Nucleic Acid Oligomer and its Conjugates with Metal-Ion-Binding Multidentate Ligands

M.J. Belousoff, G. Gasser, B. Graham, Y. Tor and L. Spiccia,* J. Biol. Inorg. Chem. 2009, 14, 287-300.


13.
Ruthenium(II) Complexes Incorporating 2-Pyridyl-2-Pyrimidine-4-Carboxylic acid

N. Nickita, G. Gasser, P. Pearson, L.Y. Goh, A.M. Bond, G.B. Deacon and L. Spiccia,* Inorg. Chem. 2009, 48, 68-81.


12.
Spectroscopic and Electrochemical Studies of Ferrocenyl Triazole Amino Acid and Peptide Bioconjugates Synthesized by Click Chemistry

S. D. Köster, J. Diettrich, G. Gasser N. Hüsken, I.C. Henao Castañeda, J.L. Jios, C.O. Della Védova, and N. Metzler-Nolte,* Organometallics, 2008, 27,6326–6332.



11.
Synthesis of Organometallic PNA Oligomers by Click Chemistry

G. Gasser, N. Hüsken, S.D. Köster and N. Metzler-Nolte,* Chem. Commun. 2008, 3675-3677.


10.
Synthesis of a Ferrocenyl Uracil PNA Monomer for Insertion into PNA Sequences

G. Gasser and L. Spiccia,* J. Organomet. Chem. 2008, 693, 2478-2482.


9.
Synthesis, Copper(II) Complexation, 64Cu-Labeling and Bioconjugation of a New Bis(2-pyridylmethyl) Derivative of 1,4,7-triazacyclonane

G. Gasser, L. Tjioe, B. Graham,* M.J. Belousoff, S. Juran, J.-U. Künstler, M. Walther, R. Bergmann, H. Stephan* and L. Spiccia,* Bioconjugate Chem. 2008, 19, 719-730.


8.
Synthesis, Structure, Spectroscopic Properties and Electrochemical Oxidation of Ruthenium(II) Complexes Incorporating Monocarboxylate Bipyridine Ligands

N. Nickita, M.J. Belousoff, A.I. Bhatt, A.M. Bond, G.B. Deacon, G. Gasser and L. Spiccia,* Inorg. Chem. 2007, 46, 8638-8651.

DOI: http://dx.doi.org/10.1021/ic700796m
7.
Products of Hydrolysis of (Ferrocenylmethyl)­trimethyl­ammonium Iodide: Synthesis of Hydroxymethylferrocene and Bis(ferrocenylmethyl) Ether

G. Gasser, A.J. Fischmann, C.M. Forsyth and L. Spiccia,* J. Organomet. Chem. 2007, 692, 3835-3840.



6.
Binding of Nitrate to a CuII-Cyclen Complex Bearing a Ferrocenyl Pendant: Synthesis, Solid State X-ray Structure and Solution Phase Electrochemical and Spectrophotometric Studies

G. Gasser, M.J. Belousoff, A.M. Bond and L. Spiccia,* Inorg. Chem. 2007, 46, 3876-3888.


5.
Recognition of Thymine and Related Nucleosides by a ZnII-Cyclen Complex Bearing a Ferrocenyl Pendant

G. Gasser, M.J. Belousoff, A.M. Bond, Z. Kosowski and L. Spiccia,* Inorg. Chem. 2007, 46, 1665-1674.


4.
Facile Synthesis and Detailed Characterization of a New Ferrocenyl Uracil Peptide Nucleic Acid Monomer

G. Gasser, M.J. Belousoff, A.M. Bond and L. Spiccia,* J. Org. Chem. 2006, 71, 7565-7573.


3.
Selective Electrochemical Sensing of Acidic Organic Molecules via a Novel Guest-to-Host Proton Transfer Reaction

H. Miyaji, G. Gasser, S.J. Green, Y. Molard, S.M. Strawbridge and J.H.R. Tucker,* Chem. Commun. 2005, 5355-5357.


2.
A Heterodifunctionalised Ferrocene Derivative that Self-assembles in Solution through Complementary Hydrogen-Bonding Interactions

H. Miyaji, M. Dudic, G. Gasser, S.J. Green, G. Labat, N. Moran, I. Prokes, H. Stoeckli-Evans, S.M. Strawbridge and J.H.R. Tucker,* Dalton Trans. 2004, 18, 2831-2832.


1.
Binding and Electrochemical Recognition of Barbiturate and Urea Derivatives by a Regioisomeric Series of Hydrogen-Bonding Ferrocene Receptors

J. Westwood, S.J. Coles, S.R. Collinson, G. Gasser, S.J. Green, M.B. Hursthouse, M.E. Light and J.H.R. Tucker,* Organometallics, 2004, 23, 946-951.



Contributions in Crystallographic Journals and in Academic Conferences

8.
 Molecular Systems for Improving Gene Mutation Corrections in Muscle Disease

R. Kapsa, G. Gasser, J. Razal, A. Quigley, T. Joshi, S. Moulton, M.J. Cook, L. Spiccia, D. Officer, G.M. Clark and G.G. Wallace, J. Gene Med. 2011, 13, 437-438.

DOI: http://dx.doi.org/10.1002/jgm.1582

7.
 2,3,5,6-Tetrakis(phenoxymethyl)pyrazine and 2,3,5,6-tetrakis(phenylsulfanylmethyl)-pyrazine

T. Assoumatine, G. Gasser and H. Stoeckli-Evans,* Acta Cryst. 2007, C63, o219-o222.

DOI: http://dx.doi.org/10.1107/S010827010700710X

6.
 2-Carbomoyl-3-pyridyl benzoate

G. Gasser and H. Stoeckli-Evans,* Acta Cryst. 2007, E63, o1421-o1422.

DOI: http://dx.doi.org/10.1107/S1600536807008112

5.
N-(Pyridine-2-carbonyl)-benzamide

G. Gasser and H. Stoeckli-Evans,* Acta Cryst. 2007, E63, o1455-01456.

DOI: http://dx.doi.org/10.1107/S1600536807008355

4.
 N-Benzoyl-N-(pyridine-2-carbonyl)-benzamide

G. Gasser and H. Stoeckli-Evans,* Acta Cryst. 2007, E63, o1518-o1520.

DOI: http://dx.doi.org/10.1107/S1600536807008884

3.
 Synthesis of New Metal Complex Biomolecule Hybrids as Redox Sensors for Specific Nucleases

G. Gasser, A.M. Bond, B. Graham, Z. Kosowski and L. Spiccia,* Proceedings of the NSTI conference, 2005, Anaheim, California, USA, May 8-12, pages 412-415.

ISBN: 0-9767985-0-6

http://www.nsti.org/procs/Nanotech2005v1/8/T68.03

2.
2,6-Dibenzyl-1,2,3,5,6,7-hexahydro-2,4,6,8-tetraaza-s-indacene and 2,6-(4-Methoxy-benzyl)-1,2,3,5,6,7-hexahydro-2,4,6,8-tetraaza-s-indacene

G. Gasser and H. Stoeckli-Evans,* Acta Cryst. 2004, C60, o514-o516.

DOI: http://dx.doi.org/10.1107/S0108270104009485


1. Di-m-chloro-bis[(2,2’:6,2’’-terpyridine-k3N)-copper(II)] diperchlorate: the triclinic polymorph

G. Gasser, G. Labat and H. Stoeckli-Evans,* Acta Cryst. 2004, E60, m244-246.

DOI: http://dx.doi.org/10.1107/S1600536804000443
Mise à jour le Dimanche, 19 Mai 2013 17:11