Enrica Bortolamiol

Enrica Bortolamiol
Exchange PhD Student
Chimie ParisTech
PSL University
CNRS
Institute of Chemistry for Life and Health Sciences
Laboratory for Inorganic Chemical Biology
+33 1 85 78 41 53
enrica.bortolamio@chimieparistech.psl.eu

Enrica was born in Vidor, a small town near Treviso in the north of Italy.

After completing the secondary school in 2012 specializing in enology and viticulture she worked in “La Tordera” winery while also attending the bachelor and master’s degree courses in Chemistry at Ca’ Foscari University in Venice. In 2016 she completed her bachelor’s degree working on the synthesis of new bisphosphonates, organic molecules against osteoporosis, in Prof. Scarso group. During her master thesis, she developed the synthesis of cationic Pd-allyl compounds bearing N-heterocyclic carbene ligands and then moved on Prof. Rizzolio group at CRO (Centro di Riferimento Oncologico) in Aviano, to study the antiproliferative activity of these complexes towards cancer cells. After graduation she obtained a research grant at CRO to investigate the primary target of palladium complexes using different immunofluorescence techniques. In 2020 she came back in chemical lab, working on Prof. Gambari’s project to synthesize organic molecules active toward β-thalassemia disease.

In November 2020 she started her PhD in Chemistry, devoting herself to the design and synthesis of new palladium compounds with different organometallic fragments as potential antiproliferative agents toward cancer cell (supervisor Prof. F. Visentin). Currently, she is working in Paris, in the laboratories of Prof. Gasser, with the aim to deepen the action mechanism study of these new metal complexes.

Enrica is dynamic and curious and in her free time she loves working hard to the gym, practice dance, swim, doing trekking, reading, and discovering new places.

Publications

[1] Bortolamiol E., Fama F., Zhang Z., Demitri N., Cavallo L., Caligiuri I., Rizzolio F., Scattolin T. and Visentin F., Cationic Palladium(II)-Indenyl complexes bearing phosphines as ancillary ligands: synthesis, study of indenyl amination and anticancer activity, 2022, submitted article

[2] Scattolin T.; Moro G.; Serena A.; Guadagnin Pattaro A.; Rizzolio F.; Canzonieri V.; Demitri N.; Bortolamiol E.; Moretto L.M.; Visentin F. Synthesis, characterization, and anticancer activity of ferrocenyl complexes bearing different organopalladium fragments in APPLIED ORGANOMETALLIC CHEMISTRY, 2022, e6629

[3] Scattolin T.; Bortolamiol E.; Rizzolio F.; Demitri N.; Visentin F. Allyl palladium complexes bearing carbohydrate-based N-heterocyclic carbenes: Anticancer agents for selective and potent in vitro cytotoxicity in APPLIED ORGANOMETALLIC CHEMISTRY, 2020, 34, e5876

[4] Scattolin T.; Bortolamiol E.; Visentin F.; Palazzolo S.; Caligiuri I.; Perin T.; Canzonieri V.; Demitri N.; Rizzolio F.; Togni A. Palladium(II)-η3-Allyl Complexes Bearing N-Trifluoromethyl N-Heterocyclic Carbenes: A New Generation of Anticancer Agents that Restrain the Growth of High-Grade Serous Ovarian Cancer Tumoroids in CHEMISTRY-A EUROPEAN JOURNAL, 2020, 26, 11868

[5] Scattolin T.; Bortolamiol E.; Caligiuri I.; Rizzolio F.; Demitri N.; Visentin F. Synthesis and comparative study of the anticancer activity of η3-allyl palladium(II) complexes bearing N-heterocyclic carbenes as ancillary ligands in POLYHEDRON, 2020,186, 114607

[6] Scattolin T.; Bortolamiol E.; Palazzolo S.; Caligiuri I.; Perin T.; Canzonieri V.; Demitri N.; Rizzolio F.; Cavallo L.; Dereli B.; Mane M.V.; Nolan S.P.; Visentin F. The anticancer activity of an air-stable Pd(i)-NHC (NHC = N-heterocyclic carbene) dimer in CHEMICAL COMMUNICATIONS, 2020, 56, 12238

[7] Scattolin T., Bortolamiol E., Visentin F., Rizzolio F., COMPLESSI DI Pd(I), PROCESSO PER LA LORO PREPARAZIONE E LORO IMPIEGO COME ANTITUMORALI, BREVETTO NUM 102019000023079, 2019, (Patent)

[8] Bortolamiol E., Chiminazzo A., Sperni L., Borsato G., Fabris F., Scarso A., Functional bisphosphonate synthesis for the development of new anti-resorption bone drug candidates in NEW JOURNAL OF CHEMISTRY, 2019, 43, 12641