Dr. Gloria Vigueras Bautista
Institute of Chemistry for Life and Health Sciences
Laboratory for Inorganic Chemical Biology
+33 1 44 27 56 04
Gloria Vigueras Bautista was born in Murcia (Spain). She studied for her bachelor’s degree in chemistry and an MSc in Fine and Molecular Chemistry at the University of Murcia. After that, she carried out her Ph.D. (2017-2021) at the same university under the supervision of Prof. José Ruiz and Dra Natalia Cutillas. Her doctoral thesis focused on the synthesis and characterization of new iridium-based compounds and the study of their potential as anti-cancer drugs in the therapy and phototherapy of cancer.
In January 2023, Gloria joined the Gasser Group at Chimie ParisTech to work on a project linked with photodynamic therapy in collaboration with Prof. José Ruiz (University of Murcia). Her postdoctoral stay is funded by the “Margarita Salas” grant of the Ministerio de Universidades (Spanish Government).
In her spare time, Gloria enjoys reading fantasy books, drawing, and writing stories.
2021: “Margarita Salas Grant for the training of young doctors”, postdoctoral research grant (Ministerio de Universidades, 2023).
2021: PhD in Inorganic Chemistry awarded with the distinction Excellent “Cum Laude” (University or Murcia, 2021).
2020: First prize of the VIII “San Alberto Magno” Poster Contest, organized by the Royal Spanish Society of Chemistry. Poster: Iridium(III) Anticancer Agents Generating Superoxide Anion Radicals: Overcoming the Achilles’ Heel of Photodynamic Therapy.
2020: First prize of the 1st edition of the “Flash Doctoral Thesis” contest, organized by the Royal Spanish Society of Chemistry.
2019: First prize of the VII “San Alberto Magno” Poster Contest, organized by the Royal Spanish Society of Chemistry. Poster: Iridium complexes to fight cancer: from darkness to light.
2018: “Highly Commended Poster Award” in the EuroBIC 14 meeting in Birmingham. Poster: Effect of Polypyridyl Ligands on the Photophysical Properties and the Photodynamic Anticancer Activity of Iridium(III) Complexes.
2017: Predoctoral research grant (FPU) from the University of Murcia (Spain).
2016: Final Degree Extraordinary Award in Chemistry
 E. Ortega-Forte, S. Hernández-García, G. Vigueras, P. Henarejos-Escudero, N. Cutillas, J. Ruiz, F. Gandía- Herrero, Potent anticancer activity of a novel iridium metallodrug via oncosis, Cell. Mol. Life Sci. 2022, 79, 510. Open Access.
 N. Busto,+ G. Vigueras,+ N. Cutillas, B. García, J. Ruiz. Inert Cationic Iridium(III) Complexes with Phenanthroline-based Ligands: Application in Antimicrobial Inactivation of Multidrug-Resistant Bacterial Strains, Dalton Trans. 2022, 51, 9653.
 J. Bonelli, E. Ortega, G. Vigueras, M. Bosch, N. Cutillas, J. Rocas, J. Ruiz, V. Marchán, Polyurethane-polyurea hybrid nanocapsules as efficient delivery systems of anticancer Ir(III) metallodrugs, Inorg. Chem. Front.., 2022, 9, 2123.
 G. Vigueras, L. Markova, V. Novohradsky, A. Marco, N. Cutillas, H. Kostrhunova, J. Kasparkova, J. Ruiz and V. Brabec, A photoactivated Ir(III) complex targets cancer stem cells and induces secretion of damage associated molecular patterns in melanoma cells characteristic of immunogenic cell death Inorg. Chem. Front., 2021, 8, 4696.
 E. Ortega, G. Vigueras, F. Ballester, J. Ruiz, Targeting Translation: a promising strategy for anticancer metallodrugs Coord. Chem. Rev., 2021, 446, 214129.
 V. Novohradsky, G. Vigueras, J. Pracharova, N. Cutillas, C. Janiak, H. Kostrhunova, V. Brabec, J. Ruiz, J. Kasparkova, Molecular superoxide radical photogeneration in cancer cells by dipyridophenazine iridium(iii) complexes Inorg. Chem. Front., 2019, 6, 2500.
 V. Novohradsky, A. Rovira; C. Hally, A. Galindo, G. Vigueras, A. Gandioso, M. Svitelova, R. Bresolí-Obach, H. Kostrhunova, L. Markova, J. Kasparkova, S. Nonell, J. Ruiz, V. Brabec, V. Marchán, Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated IrIII Complex Conjugated to a Far-Red Emitting Coumarin, Angew. Chem. Int. Ed., 2019, 58, 6311.
 J. Pracharova, G. Vigueras, V. Novohradsky, N. Cutillas, C. Janiak, H. Kostrhunova, J. Kasparkova, J. Ruiz, V. Brabec, Exploring the Effect of Polypyridyl Ligands on the Anticancer Activity of Phosphorescent Iridium(III) Complexes: From Proteosynthesis Inhibitors to Photodynamic Therapy Agents, Chem. Eur. J 2018, 24, 4607.
 A. Zamora, G. Vigueras, V. Rodríguez, M. D. Santana, J. Ruiz. Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy, Coord. Chem. Rev., 2018, 360, 34.
 J. Yellol, S. Perez, G. Yellol, J. Zajac, A. Donaire, G. Vigueras, V. Novohradsky, C. Janiak, V. Brabec, J. Ruiz. Highly potent extranuclear-targeted luminescent iridium(iii) antitumor agents containing benzimidazole-based ligands with a handle for functionalization, Chem. Commun., 2016, 52, 14165.