Kevin Cariou

Short Bio:

Kevin graduated from Chimie ParisTech in 2002, he received his PhD in 2006 from the University Pierre and Marie Curie (now Sorbonne University) in Paris (France) under the supervision of Prof. M. Malacria and L. Fensterbank, where he studied platinum- and gold-catalyzed transformations with a joint CNRS-Sanofi BDI fellowship.

From 2007 to 2009, including one-year as a Lavoisier fellowship holder, he
worked as a postdoctoral researcher in the group of Prof. A. J. Frontier at the University of Rochester (NY, USA) in the field of total synthesis.

He was appointed a Chargé de Recherche in 2009 at the CNRS at the ICSN in the team Synthesis and Methodology Applied to Research in Therapeutics (SMART) led by Dr R. H. Dodd. He obtained his Habilitation à Diriger les Recherches (HDR) in 2015. From 2017 to 2019, he was the leader of the SMART team before moving to Chimie ParisTech in 2020. During this period, his research interest was mostly focused on the development of new synthetic methods, with a focus on iodine(III) reagents and nitrogen-rich building blocks, and their application toward the synthesis of biologically active molecules, in particular antibacterials.

In January 2020 he officially joined the group of Gilles Gasser and in 2021 he was appointed CNRS Research Director. Since then, he has been particularly involved in the fields of organometallic chemistry (especially metallocenes), the design of anti-infective agents (antifungals and antiparasitics), and the use of first-line metals (iron, copper, cobalt, etc.) for anticancer applications. More generally, his expertise in organic chemistry and multistep synthesis is essential and complements that of other team members when it comes to designing particularly complex ligands, such as those incorporating fragments for biological targeting, for example.

Kevin listens to a lot of music (often with loud guitars) and enjoy spending some time in the outside, preferentially near the ocean (if possible within the waves), two passions he tries to share with his two kids.

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Recent publication

 85. Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs C. Ludwig, A.C. Taki, J.J. Byrne, P. Mesdom, O. Blacque, C. Häberli, T. Zumkehr, G. Scalese, L. Pérez-Díaz, D. Gambino, B. Lundström-Stadelmann, J. Keiser,* R.B. Gasser,* K. Cariou,* and G. Gasser,* ChemBioChem, 2026, 27, e70490. DOI: http://dx.doi.org/10.1002/cbic.70490

84. Leveraging Morphological Profiling for Mechanistic Elucidation of Metal-based Anticancer Compounds B. Park, S. Harrypersad, A. Houshmand, A. Kumar, J.C. Setiawan, A. Darracq, G. MacNeil, T. Gbadebo, K. Cariou, A. Casini, M. Contel, M. Dalla Pozza, Y. Dou, F. Figueiredo, G. Gasser, M. Guo; J. López-Hernández, W. Kandioller, J. Karges, C. Kowol, M. Malarek, S. Meier-Menches, S. Nolan, A. Notaro, J. Pankovich, K. Purkait, N. Raynal, N. Tzouras, R. Vinck, J. Wilson, A. Zucca, B. Keppler, C. Walsby,* M. Bazett,* JACS Au, 2026, 6, 3790–3803. DOI: https://doi.org/10.1021/jacsau.6c00363

83.  An Atomically Dispersed Cu Photocatalyst for the Synthesis of Trifluoromethylated Ferrocenes C. Ludwig, S. Pradhan, A. Lomas Neff, S. Das,* K. Cariou,* and G. Gasser,* Organometallics, 2026, 45, 1473-1476. DOI: https://doi.org/10.1021/acs.organomet.6c00140

82. Re(I) Tricarbonyl Multifunctional Complexes: Effects on Trypanosoma cruzi, Trypanosoma brucei, Leishmania infantum and Tumor Cells G. Scalese,* M. Soba, Y. Zhang, D. Benítez, I. Machado, L. Pérez-Díaz, K. Cariou, G. Gasser, M. Comini, and D. Gambino,* J. Organomet. Chem., 2026, 1052, 124112-124133 (special issue for ISBOMC 2025). DOI:  10.1016/j.jorganchem.2026.124113

81. Recent Advances in the Use of Osmium Complexes as Anticancer Phototherapeutics Z. Chen, C. Culot, L. Zhou, K. Cariou,* G. Berger,* and G. Gasser,* Acc. Chem. Res., 2026, 59, 1801-1812. DOI: https://doi.org/10.1021/acs.accounts.5c00886

80. A Deep-Red-Absorbing Osmium (II) Complex as a Photosensitizer for Photodynamic Therapy inducing Immunogenic Cell Death. Y. Zhang, P. Mesdom, E. Izquierdo-García, J. António, R. Gao, B. Saubamea, J. Seguin, M. Moinard, P. Arnoux, C. Frochot, K. Cariou, B.-T. Doan, G. Gasser* Angew. Chem. Int. Ed.,2026, e8677989. DOI: https://doi.org/10.1002/anie.8677989

79. Predictive Modelling Enables Exploration of the Anticancer Potential of Ruthenium (II) Polypyridyl Complexes B. Parmelli, I. Vanlaeys, O. Blacque, P. Mesdom, K. Cariou, G. Gasser, T. Stuyver* ChemRxiv 2026. https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15000025/v1

78. Expanding the DNA damaging potential of artificial metallo-nucleases with click chemistry. A. Gibney, M. Sidarta, E. Delahunt, P. Mesdom, L. Arrué, S. KK, O. Akwasi Aning, H. Hjerpe, F. Figueiredo, K. Cariou, V. McKee, P. Johansson, S. Bhattacharya, D. Thompson, M. Wenzel, G. Gasser, F. Westerlund A. Kellett* Nat Commun 2026. just accepted https://doi.org/10.1038/s41467-026-68911-5

77. Azide as a Photolabile Ligand in Gold(I) Therapeutics J. Romano-de Gea, Z. Chen, K. A. Abhyankar, R. Scopelliti, F. Fadaei-Tirani, K. Cariou, G. Gasser,* and P.J. Dyson,* J. Organomet. Chem., 2025, 1037, 123724 (special issue for ISBOMC 2025).

76. Development of Organic and Organometallic Pyrazoline Derivatives as Dual Inhibitors of COX-2 and 25-LOX with Potential as Anticancer agent E. Navarrete, T. Caceres, P. Morales, M. Muñoz-Osses, O. Blacque, P. Mesdom, K. Cariou, F. Godoy, G. Gasser,* E. Flores,* and C. Mascayano,* J. Med. Chem.,2026, 69, 1387-1402. DOI: https://doi.org/10.1021/acs.jmedchem.5c02815

75. A Cathepsin B-Triggered CO-Releasing Molecule with a Bioavailable, Non-Toxic Metal Core for Targeted Tumor Delivery I. Cernauskiene, E. Izquierdo-García, S. Keller, H. Betts, K. Cariou, V. Marchán, G. Gasser,* and G.J.L. Bernardes,* Angew. Chem. Int. Ed.,2026, 15, e13808. DOI: http://doi.org/10.1002/anie.202513808

74. Synthesis and Multidisciplinary Preclinical Investigations of Ferrocenyl, Ruthenocenyl and Benzyl Derivatives of Thiabendazole as New Drug Dandidates against Soil Transmitted Helminth Infections T. Karpstein, A. Kalamatianou, S. Keller, P. Späne, C. Häberli,, A. Odermatt, O. Blacque, K. Cariou,* G. Gasser,* and J. Keiser,* ACS Infect. Dis., 2025, 11, 2037-2047. https://doi.org/10.1021/acsinfecdis.5c00340

73. Multidisciplinary Preclinical Investigations on Ferrocenyl, Ruthenocenyl and Benzyl Derivatives of Niridazole as New Drug Candidates against Schistosomiasis T. Karpstein, S. Zhong, S. Keller; P. Späne, C, Häberli, G. Panic, O. Blacque; A. Odermatt, K. Cariou, G. Gasser,* and J. Keiser,* ChemMedChem, 2025, 20, e202500603. DOI: https://doi.org/10.1002/cmdc.202500603

72. Encapsulating NHC‐capped Copper(I) Complexes inside Cyclodextrin for Catalysis in Living Cells Figueiredo, H. Madec, P. Mesdom, G. Salluce, Y. Tigherghar, K. Cariou,* S. Roland,* M. Sollogoub,* and G. Gasser,* Chem. Sci.,2025, 16, 19727 -19736. DOI: https://doi.org/10.1039/D5SC04711K

71. Molecular and cellular effects of hydroxy-1,4 naphthoquinones used in dermatological and cosmetic applications on human protein tyrosine phosphatase PTP1B in human keratinocytes Arnaud, C. Michail, J. Gudin de Vallerin, H. Liang, X. Xu, J. Dairou, K. Cariou, J.-M. Dupret, M. Viguier, F. Rodrigues-Lima, F. Deshayes* Mol. Pharmacol.,2025, 107 100050. DOI: https://doi.org/10.1016/j.molpha.2025.100050

70. Synthesis of 1,2-Fluorinated Ferrocenes and 1,3-Fluorinated Ferrrocenes C. Ludwig, A. Massiot, E. Dolcher, O. Blacque, K. Cariou,* and and G. Gasser,* Organometallics,2025, 44, 2182. DOI: https://doi.org/10.1021/acs.organomet.5c00209 

69. Synthesis, Characterization, and Biological Evaluation of Iron(III)-N-Heterocyclic Carbene Complexes as Photosensitizers for Photodynamic Therapy and Chemotherapeutics against CancerL. Zhou, G. Salluce, P. Mesdom, M. Redrado, L. Gourdon-Grünewaldt, S. Hidalgo, O. Blacque, P. Arnoux, C. Frochot, K. Cariou,* and G. Gasser,* Inorg. Chem., 2025, 64, 17058. DOI: https://doi.org/10.1021/acs.inorgchem.5c03185

68. Guided by Enzymes: Targeted Photodynamic Therapy as a Strategy for Precision Medicine L.S. Wild, J. Whitcher, T. Rossel,* K. Cariou* and G. Gasser,* Chimia, 2025, 79, 838 DOI: https://doi.org/10.2533/chimia.2025.838

67. Synthesis and Biological Evaluation of Itraconazole Derivatives: Design in an Old Scaffolds S. Zhong, A. Kalamatianou, G. Scalese, C. O’Beirne, M. Redrado, O. Blacque, C. Tomasoni, C. Logé, M. lbassier, I. Ourlac-Garnier, F. Pagniez, P. Le Pape, L. Pérez-Díaz, D. Gambino, M.A. Comini, K. Cariou,* and G. Gasser,* Inorg. Chem., 2025, 64, 16192.DOI https://doi.org/10.1021/acs.inorgchem.5c02730 

66. Phototoxicity of Hydroxymethyl-BODIPYs: Are Photocages That Innocent? K.M. Kuznetsov, P. Mesdom, K. Purkait, O. Blacque, A.H. Winter,* K. Cariou,* and G. Gasser,* Chem. Sci.,2025, 16, 14553 DOI: https://doi.org/10.1039/D5SC04032A 

65. Synthetic strategies for the incorporation of metallocenes into anti-infective scaffolds A. Kalamatianou, C. Ludwig, S. Zhong, K. Cariou* and G. Gasser* Chem. Soc. Rev., 2025, 54, 3930 10.1039/D4CS01216J. Metal-Catalyzed Cross-Coupling for the Synthesis of β-Lactam Drugs and Related Chemical Probes

64. Bresson, K. Burke, M. Ethève-Quelquejeu, L. Iannazzo,* K. Cariou,* ChemMedChem, 2025, 20,  e202400960 part of the special collection “Drug Discovery in France” 10.1002/cmdc.202400960.

63. Development of Ferrocenyl and Ruthenocenyl Zileuton Analogs with Enhanced Bioactivity toward Human 5-Lipoxygenase: Innovation in Drugs for Inflammatory Diseases Navarrete, P. Morales, T. Caceres, A. Vega, P. Mesdom, K. Cariou, F. Godoy, G. Gasser,* E. Flores,* C. Mascayano* Inorg. Chem., 2025, 64, 3495–3505.

62. Antifungal and Antiparasitic Activity of Novel Metallocene-containing Fluconazole Derivatives
Y. Lin, G. Scalese, C.A. Bulman, R. Vinck, O. Blacque, M. Paulino, A. Ballesteros-Casallas, L. Pérez Díaz, G. Salinas, M. Mitreva,* T. Weil,* K. Cariou,* J.A. Sakanari,* D. Gambino,* and G. Gasser,* ACS Infect. Dis., 2024, 10, 938–950.

61. Two in One: Merging Photoactivated Chemotherapy and Photodynamic Therapy to Fight Cancer Kuznetsov, K. Cariou* and G. Gasser Chem. Sci., 2024, 15, 17760–17780.

60. EGCG-like non-competitive inhibitor of DYRK1A rescues cognitive defect in a down syndrome model M. Delabar,* M. A. GB Gomes, M. Fructuoso, N. Sarrazin, N. George, N. Fleary-Roberts, H. Sun, L. Chi Bui, F. Rodrigues-Lima, N. Janel, J. Dairou, E. J Maria, R. H Dodd, K. Cariou,* M.-C. Potier* Eur. J. Med. Chem., 2024, 265, 116098.

59. Discovery of New Broad-Spectrum Anti-Infective Agents Based on Bioorganometallic Chemistry Lin, H. Jung, C.A. Bulman, J. Ng, R. Vinck, C. O’Beirne, S. Zhong, M.S. Moser, N. Tricoche, R. Peguero, R. Li, J.F. Urban Jr, P. Le Pape, F. Pagniez, M. Moretto, T. Weil,* S. Lustigman,* K. Cariou,* M. Mitreva,* J.A. Sakanari* and G. Gasser,* J. Med. Chem., 2023, 6, 15867–15882.

58. BASHY Dyes Are Highly Efficient Lipid Droplet-targeting Photosensitizers That Induce Ferroptosis Through Lipid Peroxidation Silva, Y. Zhang, R. Vinck, F. Santos, J. António, L. Gourdon-Grünewaldt, C. Zaouter, A. Castonguay, S. Patten, K. Cariou, F. Bosca, F. Najera, J. Arteaga, G. Gasser*, U. Pischel*, P. Gois* Bioconjug. Chem. 2023, 34, 2337-2344.

57. Ru(ii)/Os(ii)-based carbonic anhydrase inhibitors as photodynamic therapy photosensitizers for the treatment of hypoxic tumours Wang, P. Mesdom, K. Purkait, B. Saubaméa, P. Burckel, P. Arnoux, C. Frochot, K. Cariou,* T. Rossel,* G. Gasser* Chem Sci. 2023, 14, 11749-11760.

56. Towards Ruthenium (II)‐Rhenium (I) Binuclear Complexes as Photosensitizers for Photodynamic Therapy Wang, P. S. Felder, P. Mesdom, O. Blacque, T. L. Mindt, K Cariou, G. Gasser* ChemBioChem, 2023, 24, e202300467.

55. Towards Copper (I) Clusters for Photo‐Induced Oxidation of Biological Thiols in Living Cells L Gourdon-Grünewaldt, O Blacque, G Gasser*,

54. In Situ Bioconjugation of a Maleimide-Functionalized Ruthenium-Based Photosensitizer to Albumin for Photodynamic Therapy R Vinck, O Dömötör, J Karges, M Jakubaszek, J Seguin, M Tharaud, V. Guérineau,

53. Towards Platinum(II) Complexes for in cellulo Applications: Synthesis, Characterization, Biological and Catalytic Evaluation L Gourdon‐Grünewaldt, M Bakija, L Wild, B Perić, G Gasser, SI Kirin, .K. Cariou* Helv. Chim. Act. 2023, 106, e202300078.

52. PSL Chemical Biology Symposia Third Edition: A Branch of Science in its Explosive Phase L Baron, [ 43 authors], R. Rodriguez

51. Synthesis, characterisation and biological evaluation of monometallic Re (i) and heterobimetallic Re (i)/Fe (ii) complexes with a 1, 2, 3-triazolyl pyridine chelating moiety Jakopec, L. Gourdon-Grünewaldt, I. Čipor, A. Meščić Macan, B. Perić, I. Piantanida, K. Cariou, G. Gasser,* S. I Kirin,* S. Raić-Malić* Dalton Trans. 2023, 52, 9482-9498.

50. Structurally Simple Osmium(II) Polypyridyl Complexes as Photosensitizers for Photodynamic Therapy in the Near InfraredMani, T. Feng, A. Gandioso, R. Vinck, A. Notaro, L. Gourdon‐Grünewaldt, P. Burckel, B. Saubaméa, O. Blacque, K. Cariou, J.-E. Belgaied, H. Chao and G. Gasser,* Angew. Chem. Int. Ed. 2023, accepted doi: 10.1002/anie.202218347.

49. Metal Complexes for (Photo-)catalytic Reactions in Living Cells and Organisms
Madec, F. Figueiredo, K. Cariou, S. Roland, M. Sollogoub and G. Gasser,* Chem. Sci 2023, 14, 409–442.
DOI: http://doi.org/10.1039/D2SC05672K OPEN ACCESS

48. N-Metallocenyl Ynamides: Preparation, Reactivity, and Synthesis of ansa[3]-Ferrocenylamides
Mahe, O. Blacque, V. Gandon, G. Gasser and K. Cariou* 2023, Org. Lett. 2023, 25, 624–629.
DOI: https://doi.org/10.1021/acs.orglett.2c04169

47. Red-Absorbing Ru(II) Polypyridyl Complexes with Biotin Targeting Spontaneously Assemble into Nanoparticles in Biological Media
Vinck, A. Gandioso, P. Burckel, B. Saubaméa, K. Cariou and G. Gasser* Inorg. Chem. 2022, 13576–13585.
DOI: http://dx.doi.org/10.1002/cbic.202200398 OPEN ACCESS

46. Base-Mediated Generation of Ketenimines from Ynamides: Addition of Hydrazones to Give Acetimidohydrazides
Mahe; A. C. A. D’Hollander and K. Cariou* Eur. J. Org. Chem. 2022, e202200028.
DOI: https://doi.org/10.1002/ejoc.202200028 OPEN ACCESS

45. Organometallic Derivatives of Decoquinate targeted towards Toxoplasma gondii
H.D. Betts, Y.C. Ong, N. Anghel, S. Keller, J. Karges, N. Voutsara, J. Müller, E. Manoury, O. Blacque, K. Cariou, A. Hemphill* G. Gasser* Organometallics 2022, 41, 2035–2041.DOI: https://doi.org/10.1021/acs.organomet.2c00204

44. Phototherapeutic Strategies with First-Row Transition Metal Complexes: a Critical Review
Gourdon, K. Cariou* and G. Gasser* Chem. Soc. Rev., 2022, 51, 1167–1195.
DOI: http://dx.doi.org/10.1039/d1cs00609f OPEN ACCESS

43. Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the Spike/ACE2 Interaction and the Papain-like Protease PLpro
M. Gil-Moles, S. Türck, U. Basu, A. Pettenuzzo, S. Bhattacharya, A. Rajan, X. Ma, R. Büssing, J. Wölker, H. Burmeister, H. Hoffmeister, P. Schneeberg, A. Prause, P. Lippmann, J. Kusi-Nimarko, S. Hassell-Hart, A. McGown, D. Guest, Y. Lin, A. Notaro, R. Vinck, J. Karges, K. Cariou, K. Peng, X. Qin, X. Wang J. Skiba, Ł. Szczupak, K. Kowalski, U. Schatzschneider, C. Hemmert, H. Gornitzka, E.R. Milaeva, A.A. Nazarov, G. Gasser, J. Spencer; L. Ronconi, U. Kortz, J. Cinatl, D. Bojkova and I. Ott,* Chem. Eur. J., 2021, 27, 17928-17940.
DOI: https://doi.org/10.1002/chem.202103258 OPEN ACCESS

.42. Recent Developments of Metal-based Compounds against Fungal Pathogens
Y. Lin, H. Betts, S. Keller, K. Cariou,* and G. Gasser,* Chem. Soc. Rev., 2021, 50, 10346-10402.
DOI: https://doi.org/10.1039/D0CS00945H

41. Physical, Spectroscopic, and Biological Properties of Ruthenium and Osmium Photosensitizers Bearing Diversely Substituted 4,4′-di(styryl)-2,2′-bipyridine Ligand
R. Vinck, J. Karges, M. Tharaud, K. Cariou and G. Gasser,* Dalton Trans., 2021, 50, 14629-14639.
DOI: http://dx.doi.org/10.1039/D1DT02083H

40. In vivo Active Organometallic-containing Antimycotic Agents
R. Rubbiani,* T. Weil,* N. Tocci, L. Mastrobuoni, S. Jeger, M. Moretto, J. Ng, Y. Lin J. Hess, S. Ferrari, A. Kaech, L. Young, J. Spencer, A. L. Moore, K. Cariou,* R. Giorgia, L. Romani, M. Pariano and G. Gasser,* RSC Chem. Biol., 2021, 2, 1263-1273.
DOI: https://doi.org/10.1039/D1CB00123J

39. Base-Mediated Generation of Ketenimines from Ynamides: [3+2] Annulation with Azaallyl Anions
D’Hollander, A. C. A.;  Romero, E.; Vijayakumar, K.; Le Houérou, C.; Retailleau, P.; Dodd, R. H.; Iorga, B. I.; Cariou, K.* Adv.Synth. Cat. 2021; 362, 2903–2908.
DOI: https://doi.org/10.1002/adsc.202100047

38. Photoinduced Aerobic Iodoarene-Catalyzed Spirocyclization of N-Oxy-Amides to N-Fused Spirolactams Habert, L.; Cariou, K. Angew. Chem. Int. Ed., 2021; 60, 171–175. https://doi.org/10.1002/anie.202009175; preprint: DOI: 10.26434/chemrxiv.12562355.v1

37. Ynamides in Free Radical Reactions Mahe, C.; Cariou, K.*Adv.Synth. Cat. 2020; 362, 4820–4832. https://doi.org/10.1002/adsc.202000849.

36. Azetidinimines as a Novel Series of Non-Covalent Broad-Spectrum Inhibitors of β-Lactamases with Submicromolar Activities Against Carbapenemases of Classes A, B and D  Romero, E.; Oueslati, S.; Benchekroun, M.; D’Hollander, A. C. A.; Ventre S.; Vijayakumar, K.; Minard, C.; Exilie, C.; Tlili, L.; Retailleau, P.; Zavala, A.. Eliséee, E.; Selwa, E.. Nguyen, L. Pruvost, A.; Naas, T.;* Iorga, B.;* Dodd, R. H.; Cariou, K.* Eur. J. Med. Chem. 2021, 219 113418. https://doi.org/10.1016/j.ejmech.2021.113418

35. Synthesis, Characterization and Antiparasitic Activity of Organometallic Derivatives of the Anthelmintic Drug Albendazole
Y. Lin, Y.C. Ong, S. Keller, J. Karges, R. Bouchene, E. Manoury, O. Blacque, J. Müller, N. Anghel, A. Hemphill, C. Häberli, A.C. Taki, R.B. Gasser, K. Cariou,* J. Keiser,* and G. Gasser,* Dalton Trans., 2020, 49, 6616-6626.

34. Synthetic approaches towards avibactam and other diazabicyclooctane β-lactamase inhibitors Peilleron, L.; Cariou, K.* Org. Biomol. Chem. 2020, 18, 830-844

33. A tutorial for the assessment of the stability of organometallic complexes in biological media Keller, S.; Ong, Y. C.; Lin Y.; Cariou, K.;* Gasser, G.* J. Organomet. Chem. 2020, 906, 121059.

32. Synthesis of Cyclic N‐Hydroxylated Ureas and Oxazolidinone Oximes Enabled by Chemoselective Iodine(III)‐Mediated Radical or Cationic Cyclizations of Unsaturated N‐Alkoxyureas Peilleron, L.; Retailleau, P.; Cariou, K.*  Adv. Synth. Cat. 2019; 361, 1753–1769.

31. Halonium-Induced Polyene Cyclizations D’Hollander, C. A.; Peilleron, L.; Grayfer, T. D.; Cariou, K.* Synthesis 2019; 51, 5160–5169. (Invitation for a “Short Review”).

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Publications from before 2019:

1. Iodine(III)-mediated halogenations of acyclic monoterpenoids Peilleron, L.; Grayfer, T. D.; Dubois, J.; Dodd, R. H.; Cariou, K.* Beilstein J. Org. Chem. 2018, 14, 1103–1111. (Invitation for the Thematic Series “Hypervalent iodine chemistry in organic synthesis”, Guest Editor T. Wirth).
2. DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives Neumann, F.; Gourdain, S.; Albac, C.; Dekker, A. D.; Bui, L. C.; Dairou, J.; Schmitz-Afonso, I.; Hue, N.; Rodrigues-Lima, F.; Delabar, J. M.; Potier, M.-C.; Le Caër, J.-P.; Touboul, D.; Delatour, B.; Cariou, K.; Dodd, R. H.* Scientific Reports, 2018, 8, Article number: 2859.
3. Ketenimines Generated from Ynamides : Versatile Building Blocks for Nitrogen-Containing Scaffolds R. H. Dodd, Cariou, K.*, Chem. Eur. J. 2018, 24, 2297–2304. (Invitation for a “Concept”):
4. Base-Mediated Generation of Ketenimines from Ynamides: Direct Access to Azetidinimines by an Imino Staudinger Synthesis Romero, E.; Minard, C.; Benchekroun, M.; Ventre, S.; Retailleau, P.; Dodd, R. H.*; Cariou, K.* Chem. Eur. J. 2017, 23, 12991–12994; (Hot Paper, Inside Cover, Highlighted in SYNFACTS)
5. Chemodivergent, Tunable, and Selective Iodine(III)-Mediated Bromo-Functionalizations of Polyprenoids Grayfer, T. D.; Retailleau, P.; Dodd, R. H.; Dubois, J.; Cariou, K.* Org. Lett. 2017, 19, 4766–4769.
6. Synthesis of Orthogonally N-Protected, C-4 Functionalized Cyclic Guanidines from l-Serine Silva, D. R. C.; Maria, E. J.; Suárez Ordóñez, R. M.; Thierry, J.; Cariou, K.*; Dodd, R. H.* Synlett 2017, 28, 815–818.
7. Assessing Ligand and Counterion Effects in the Noble Metal Catalyzed Cycloisomerization Reactions of 1,6-Allenynes: a Combined Experimental and Theoretical Approach Jaroschik, F.; Simonneau, A.; Lemière, G.; Cariou, K.; Agenet, N.; Amouri, H.; Aubert, C.; Goddard, J.-P.; Lesage, D.; Malacria, M.; Gimbert, Y.*; Gandon, V.*; Fensterbank, L.* ACS Catal., 2016, 6, 5146–5160
8. PIFA-mediated ethoxyiodination of enamides with potassium iodide Beltran, R.; Nocquet-Thibault, S.; Blanchard, F.; Dodd, R. H.*; Cariou, K.* Org. Biomol. Chem. 2016, 14, 8448–8451.
9. Mallotojaponins B and C: Total Synthesis, Antiparasitic Evaluation, and Preliminary SAR Studies Grayfer, T. D.; Grellier, P.; Mouray, E.; Dodd, R. H.; Dubois, J.*; Cariou, K.* Org. Lett. 2016, 18, 708–711.
10. Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogens Duval, R.; Xu, X.; Bui, L. C.; Mathieu, C.; Petit, E.; Cariou, K.; Dodd, R. H.; Dupret, J.-M.; Rodrigues-Lima, F.* Oncotarget 2016, 7, 8688–8699. 
11. Halocyclization of Unsaturated Guanidines Mediated by Koser’s Reagent and Lithium Halides Daniel, M.; Blanchard, F.; Nocquet-Thibault, S.; Cariou, K.*; Dodd, R. H.* J. Org Chem. 2015, 80, 10624–10633. 
12. Iodine(III)-mediated Diazidation and Azido-Oxyamination of Enamides Nocquet-Thibault, S.; Rayar, A.; Retailleau, P.; Cariou, K.*; Dodd, R. H.* Chem. Eur. J. 2015, 21, 14205–14210.
13. Iodine(III)-mediated ethoxychlorination of enamides with iron(III) chloride Nocquet-Thibault, S.; Minard, C.; Retailleau, P.; Cariou, K.; Dodd, R. H.* Tetrahedron 2014, 70, 6769–6775.
14. Transition-Metal-Free Tunable Chemoselective N-Functionalization of Indoles with Ynamides Hentz, A.; Retailleau, P.; Gandon, V.; Cariou, K.; Dodd, R. H.* Angew. Chem. Int. Ed., 2014, 53, 8333–8337.
15. Selective Suzuki- Miyaura Monocouplings with Symmetrical Dibromoarenes and Aryl Ditriflates for the One- Pot Synthesis of Unsymmetrical Triaryls Minard, C.; Palacio, C.; Cariou, K.; Dodd, R. H.* Eur. J. Org. Chem. 2014, 2942–2955.
16. Development of DANDYs, New 3,5-Diaryl-7-azaindoles Demonstrating Potent DYRK1A Kinase Inhibitory Activity Gourdain, S.; Dairou, J.; Denhez, C.; Bui, L. C.; Rodrigues-Lima, F.; Janel, N.; Delabar, J. M.; Cariou, K.; Dodd, R. H.* J. Med. Chem. 2013, 56, 9569–9585.
17. Iodine(III)-Mediated Umpolung of Bromide Salts for the Ethoxybromination of Enamides Nocquet-Thibault, S.; Retailleau, P.; Cariou, K.; Dodd, R. H.* Org. Lett. 2013, 15, 1842–1845.
18. Copper(I) Catalyzed Regioselective Asymmetric Alkoxyamination of Aryl Enamide Derivatives Nakanishi, M.; Minard, C.; Retailleau, P.; Cariou, K.; Dodd, R. H.* Org. Lett. 2011, 13, 5792–5795.
19. A Macrocyclic β-Iodoallenolate Intermediate is Key: Synthesis of the ABD Core of Phomactin A Ciesielski, J.; Cariou, K.; Frontier, A. J.* Org. Lett. 2012, 14, 4082–4085.
20. Total Synthesis of (+/-)-Rocaglamide via Oxidation-Initiated Nazarov Cyclization Malona, J. A.; Cariou, K.; Spencer, W. T. III; Frontier, A. J.* J. Org. Chem. 2012, 77, 1891–1908.
21. New elements in the gold(I)-catalyzed cycloisomerization of enynyl ester derivatives embedding a cyclohexane template Harrak, Y.; Makhlouf, M.; Azzaro, S.; Mainetti, E.; Cariou, K.; Gandon, V.; Goddard, J.-P.; Malacria, M.; Fensterbank, L.* J. Organomet. Chem. 2011, 696, 388–399.
22. Nazarov Cyclization Initiated by Peracid Oxidation: The Total Synthesis of (+/-)-Rocaglamide Malona, J. A.; Cariou, K.; Frontier, A. J.* J. Am. Chem. Soc. 2009, 131, 7560–7561.
23. Generation and Trapping of Cyclopentenylidene Gold Species: Four Pathways to Polycyclic Compounds Lemière, G.; Gandon, V.*; Cariou, K.; Hours, A.; Fukuyama, T.; Dhimane, A.-L.; Fensterbank, L.*; Malacria, M.* J. Am. Chem. Soc. 2009, 131, 2993–3006.
24. Tandem Gold(I)-catalyzed Cyclization / Electrophilic Cyclopropanation of Vinyl Allenes Lemière, G.; Gandon, V ; Cariou, K.; Fukuyama, T.; Dhimane, A.-L.; Fensterbank, L.; Malacria, M.* Org. Lett., 2007, 9, 2207–2209.
25. From PtCl₂– and Acid- Catalyzed to Uncatalyzed Cycloisomerization of 2-Propargyl Anilines: Access to Functionalized Indoles Cariou, K.; Ronan, B.; Mignani, S.; Fensterbank, L.*; Malacria, M.* Angew. Chem. Int. Ed., 2007, 46, 1881–1884.
26. New Unsaturated Amino Acids Containing an Allylsilane Moiety on the Lateral Chain Reginato, G.*; Mordini, A.; Meffre, P.; Tenti, A.; Valacchi, M.; Cariou, K. Tetrahedron: Asymmetry 2006, 17, 922–926.
27. PtCl₂ and PtCl₄-Catalyzed Cycloisomerizations of Polyunsaturated precursors Marco-Contelles, J.; Arroyo, N.; Anjum, S.; Mainetti, E.; Marion, N.; Cariou, K.; Lemière, G.; Mouriès, V.; Fensterbank, L.*; Malacria, M.* Eur. J. Org. Chem. 2006, 4618–4633.
28. Tandem PtCl₂-Catalyzed-Thermal [3,3] Rearrangements of Enyne Acetates Cariou,K.; Mainetti, E.; Fensterbank, L.; Malacria, M. Tetrahedron 2004, 60, 9745–9755.
29. PtCl₂-Catalyzed Cycloisomerizations of 5-En-1-yn-3-ol Systems Harrak, Y.; Blaszykowski,C.; Bernard, M.; Cariou, K.; Mainetti, E.; Mouries, V.; Dhimane, A.-L.*; Fensterbank, L.*; Malacria, M.* J. Am. Chem. Soc. 2004, 126, 8656–8657.
30. PtCl₂-Catalyzed Cycloisomerizations of Allenynes Cadran, N.; Cariou, K.; Hervé, G.; Aubert, C.; Fensterbank, L.*; Malacria, M.*; Marco-Contelles, J. J. Am. Chem. Soc. 2004, 126, 3408–3409.

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