Marcos Palmeira-Mello

Marcos V. Palmeira-Mello
Exchange PhD Student
Chimie ParisTech
PSL University
Institute of Chemistry for Life and Health Sciences
Laboratory for Inorganic Chemical Biology
+33 1 85 78 41 53

Marcos was born in São Gonçalo, Rio de Janeiro state (Brazil). During his bachelor’s degree, he worked with Molecular Modeling of bioactive compounds under the supervision of Prof. Alessandra Souza, at Universidade Federal Fluminense. He carried out a PhD (2016-2020) at the same university under supervision of Prof. Mauricio Lanznaster. His doctoral thesis focused on the study of cobalt(III) complexes as possible hypoxia activated prodrugs. As part of him thesis work, he spent six months at nanoBIC research group, at the Universitat de Barcelona (Spain), investigating DNA-interacting properties of different metal-based compounds, under supervision of Prof. Patrick Gamez.

In September 2021, he started a 2-year post-doc at the group of Prof. Alzir Batista, at the Universidade Federal de São Carlos, São Paulo (Brazil), studying Ruthenium(II)/phosphine complexes as possible anticancer agents. In February 2023, Marcos joined the Gasser Group at Chimie Paris Tech to work on the project “Investigation of Ruthenium(II)-based Complexes as Chemotherapy Anticancer Candidates: From Design to Biological/Biochemical Studies”. His postdoctoral stay is funded by the “Research Internships Abroad – BEPE” grant of the São Paulo State Research Support Foundation (FAPESP, Brazil).

In his spare time Marcos enjoys writing, go out to listen to music and drink with friends. He also likes discovering new places and music festivals.


2022: Research Internships Abroad – BEPE, postdoctoral research grant (São Paulo State Research Support Foundation, FAPESP, Brazil, 2023).

2022: Best poster LXChemInorg category in LatinXChem Conference. Poster: Insights about the antitumor profile of novel Ru complexes containing mercapto ligands.

2018: Doctoral Sandwich research grant – PDSE (Coordination of Superior Level Staff Improvement, CAPES, Brazil).


[1]    Calixto, S.; Simão, T.L.B.V; Palmeira-Mello, M.V.; Viana, G.M.; Assumpção, P.W.M.C.;  Rezende, M.G.; Espirito Santo, C.C.; Oliveira Mussi, V.; Rodrigues, C.R.; Launskaia, E.; Souza, A.M.T.; Cabral, L.M. Muzitano, M.F. Antimycobacterial and anti-inflammatory activities of thiourea derivatives focusing on treatment approaches for severe pulmonary tuberculosis. Bioorg.Med. Chem. 2022, 53, 116506.

[2]    Fernandes, C.M.; Palmeira-Mello, M.V.; Leite, M.C.; Oliveira, J.A.M.; Martins, I.I.; De Sá, R.G.; De Almeida, L.A.; Souza, A.M.T.;Campos, V.R.; Ponzio, E.A. Corrosion inhibition and ecotoxicological assessment of 1,2,3-triazolic alcohols. Mat. Chem. Phys. 2022, 290, 126508.

[3]    Palmeira-Mello, M.V.; Caballero, A.B.; Lopez-Espinar, A.L.; Guedes, G.P.; Caubet, A.; Souza, A.M.T.; Lanznaster, M.; Gamez, P. DNA-interacting properties of two analogous square-planar cis-chlorido complexes: copper versus palladium. J. Biol. Inorg. Chem. 2021, 26, 727-740.

[4]    Palmeira-Mello, M.V.; Souza, J.L.; Pérez, A.F.; Cavalcanti, A.S.; Kahn, S.A.; Passe-Coutrin, N.; Guerra, I.R.; Domenech-Carbo, A.; Jauregui-haza, Souza, A.M.T.; Lanznaster, M.; Cebrian-Torrejón, G. Insights of Tris(2-pyridylmethyl)amine as anti-tumor agent for osteosarcoma: experimental and in silico studies. J. Mol. Struct. 2021, 1228, 129773.

[5]    Escrivani, D.O.; Charlton, R.L.; Caruso, M.B.; Burle-Caldas, G.A.; Borsodi, M.P.G.; Zingali, R.B.; Palmeira-Mello, M.V.; Jesus, J.B.; Souza, A.M.T.; Abrahim-Vieira, B.; Freitag-Pohl, S.; Pohl, E.; Denny, P.W.; Rossi-Bergmann, B.; Steel, P.G. Chalcones identify cTXNPx as a potential antileishmanial drug target. PLoS Negl. Trop. Dis. 2021, 15, e0009951.

[6]    Mello, M.V.P.; Domingos, T.F.; Ferreira, D.; Ribeiro, M.; Ribeiro, T.; Rodrigues, C.R.; Souza, A.M.T. Antiviral drug discovery and development for Mayaro Fever – What do we have so far?. Mini-Rev. Med. Chem. 2020, 20, 921-928.

[7]    Palmeira-Mello, M.V.; Caballero, A.B.; Ribeiro, J.M.; Souza-fagundes, E.M.; Gamez, P. Lanznaster, M. Evaluation of cobalt(III) complexes as potential hypoxia-responsive carriers of esculetin. J. Inorg. Biochem. 2020, 211, 111211.

[8]    Fernandes, C.M.; Mello, M.V.P.; Santos, N.E.; Souza, A.M.T.Lanznaster, M. Ponzio, E.A. Theoretical and experimental studies of a new aniline derivative corrosion inhibitor for mild steel in acid medium. MAT. Corr. Sci. 2020, 71, 280-291.

[9]    Mello, M.V.P.;  Silva, A.F.M.; Gomez, J.G.; Ferreira, G.B.; Lanznaster, M. Investigation of cobalt(III)-tetrachlorocatechol complexes as models for catechol-based anticancer prodrugs. Eur. J. Inorg. Chem. 2019, 1784-1791.

[10] Mello, M.V.P.; Cebrian-Torrejon, G.; Pereira, J.R.; Santos Moreira, C.; Gomes, C.B.S.M.R.; Rocha, D.R.; Souza-Fagundes, E.M.; Ferreira, G.B.; Lanznaster, M. Evaluation of 5-hydroxy-1,4-naphthoquinone-cobalt(III) complexes for hypoxia-activated drug delivery. J. Inorg. Biochem. 2019, 110756.

[11]  Mello, M.V.P.; Abrahim-Veira, B.A.; Domingos, T.F.S.; Jesus, J.B.; Sousa, A.C.C.; Rodrigues, C.R.; Souza, A.M.T. A comprehensive review of chalcone derivatives as antileishmanial agents. Eur.J. Med. Chem. 2018, 150, 920-929.

[12]  Amorim, R.; Meneses, M.D.F.; Borges, J.C.; Pinheiro, L.C.S.; Caldas, L.A.; Cirne-Santos, C.C.; Mello, M.V.P.; Souza, A.M.T.; Castro, H.C.; Paixão, I.C.N.P.; Campos, R.M.; Bergmann, I.E.; Malirat, V.; Bernardino, A.M.R.; Rebello, M.A.; Fernandes, D.F.  Thieno[2,3-b]pyridine derivatives: a new class of antiviral drugs against Mayaro virus. Arch. Virol. 2017, 163, 1577-1587.

[13] Ventura, T.; Calixto, S.; Abrahim-Vieira, B.A.; Souza, A.M.T.; Mello, M.V.P.; Rodrgiues, C.R.; Mariz e Miranda, L.S.; Souza, R.A.; Leal, I.; Lasunkaia, E.; Muzitano, M.  Antimycobacterial and Anti-Inflammatory Activities of Substituted Chalcones Focusing on an Anti-Tuberculosis Dual Treatment Approach. Molecules, 2015, 20, 8072-8093.