Marta Martinez Alonso
Post-doctoral Fellow
Chimie ParisTech
PSL University
CNRS
Institute of Chemistry for Life and Health Sciences
Laboratory for Inorganic Chemical Biology
+33 1 44 27 56 04
m.martinez-alonso@chimieparistech.psl.eu
Marta was born in Burgos, a cold but beautiful city in the north of Spain. She studied Chemistry at the University of Burgos, and then, a MSc in Advanced Chemistry in the same university. After these years, she found out she wanted to lead her career towards research, so she decided to start a PhD program with Dr. Gustavo Espino in the synthesis and characterization of Ru(II), Ir(III) and Rh(III) complexes with applications in chemotherapy, LEC devices and photocatalysts. In the years as a PhD student, she did a 3 months placement with Prof. Eric Meggers’ group at Phillips-Universität Marburg, trying to prepare some Ir(III) complexes for bioorthogonal synthesis for cancer research. She finished the PhD in 2017, and then, in 2018, she moved to the University of Sheffield (UK) with a post-doctoral fellowship from Fundación Alfonso Martín Escudero. There, she worked with Prof. Julia Weinstein in the development of new Ir(III) complexes as photosensitizers for photodynamic therapy. Moreover, she developed some skills handling and working with cells in collaboration with Dr. Helen Bryant.
After 2 years, she moved to Paris, with a MSCA-IF to work with Dr. Gilles Gasser. Here, she’s working on the synthesis of cyclometalated Ru(II) polypyridyl complexes as photosensitizers for photodynamic therapy.
She loves dark chocolate and cheese, escape rooms, board games and travel.
Awards
2018: MSCA-IF Fellow.
2018: Extraordinary Doctorate Award.
2017: Post-doctoral fellow Fundación Alfonso Martín Escudero.
2010/2011: Collaboration Scholarship from the Spanish Government to get a first approach to research.
Publications
[1] Strong influence of the ancillary ligands containing benzothiazole or benzimidazole rings, in the cytotoxicity and photoactivation of Ru(II) arene complexes. Lari, M.; Martínez-Alonso, M.; Busto, N.; Manzano, B. R.; Rodríguez, A. M.; Acuña, M. I.; Dominguez, F.; Albasanz, J. L.; Leal, J. M.; Espino, G.; García, B. Inorg. Chem. 2018, 57, 14322-14336.
[2] Strong Influence of the Ancillary Ligand over the Photodynamic Anticancer Properties of Neutral Biscyclometalated Ir(III) Complexes Bearing 2-Benzoazole-Phenolates. Martínez-Alonso, M.; Busto, N.; Aguirre, L. D.; Berlanga, L.; Carrión, M. C.; Cuevas, J. V.; Rodríguez, A. M.; Carbayo, A.; Manzano, B. R.; Ortí, E.; Jalón, F. A.; García, B.; Espino, G. Chem. – A Eur. J. 2018, 24, 17523-17537 (Hot Paper).
[3] Thiabendazole-based Rh(III) and Ir(III) biscyclometallated complexes with mitochondria-targeted anticancer activity and metal-sensitive photodynamic activity. Pérez-Arnaiz, C.; Acuña, M. I.; Busto, N.; Echevarría, I.; Martínez-Alonso, M.; Espino, G.; García, B.; Domínguez, F. Eur. J. Med. Chem. 2018, 157, 279–293.
[4] Selective Photooxidation of Sulphides catalyzed by Biscyclometalated IrIII Photosensitizers Bearing 2,2’- dipyridylamine Based Ligands. Vaquero, M.; Ruiz-Riaguas, A.; Martínez-Alonso, M.; Jalón, F. Á.; Manzano, B. R.; Rodríguez, A. M.; García-Herbosa, G.; Aránzazu, C.; García, B.; Espino, G. Chem. – A Eur. J. 2018, 32, 60–73 (Hot paper and Inside Cover).
[5] Highly Stable and Efficient Light-Emitting Electrochemical Cells Based on Cationic Iridium Complexes Bearing Arylazole Ancillary Ligands. Martínez-Alonso, M.; Cerdá, J.; Momblona, C.; Pertegás, A.; Junquera-Hernández, J. M.; Heras, A.; Rodríguez, A. M.; Espino, G.; Bolink, H.; Ortí, E. Inorg. Chem. 2017, 56, 10298-10310.
[6] Hybrid aramids, Ir(III)-functionalized aromatic polyamides. Miguel-Ortega, A.; Trigo-López, M.; García, F. C.; Reglero, J. A.; Martínez-Alonso, M.; Espino, G.; García, J. M. European Polymer Journal 2017, 95, 119-126.
[7] Monomer–Dimer Divergent Behavior toward DNA in a Half-Sandwich Ruthenium(II) Aqua Complex. Antiproliferative Biphasic Activity. Busto, N.; Martínez-Alonso, M.; Leal, J. M.; Rodríguez, A. M.; Domínguez, F.; Acuña, M. I.; Espino, G.; García, B. Organometallics 2015, 34, 319–327.
[8] Derivation of Structure–Activity Relationships from the Anticancer Properties of Ruthenium(II) Arene Complexes with 2-Aryldiazole Ligands. Martínez-Alonso, M.; Busto, N.; Jalón, F. A.; Manzano, B. R.; Leal, J. M.; Rodríguez, A. M.; García, B.; Espino, G. Inorg. Chem. 2014, 53, 11274–112788.
[9] Anticancer Activity and DNA Binding of a Bifunctional Ru(II) Arene Aqua-Complex with the 2,4-Diamino-6-(2-pyridyl)-1,3,5-triazine Ligand. Busto, N.; Valladolid, J.; Martínez-Alonso, M.; Lozano, H. J.; Jalón, F. A.; Manzano, B. R.; Rodríguez, A. M.; Carrión, M. C.; Biver, T.; Leal, J. M.; Espino, G.; García, B. Inorg. Chem. 2013, 52, 9962–9974.
[10] Patent ES2642114 (Spain, OEPM). Complejos de iridio(III) de fórmula general [Ir(C^N)2(N^O)] o [Ir(C^N)2(N^N’)]A. Espino Ordóñez, Gustavo; Carbayo Martín, Aránzazu; García Ruiz, Begoña; Martínez Alonso, Marta; Aguirre Méndez, Larry Danilo; Berlanga Sanz, Leticia; Galerón Rodríguez, Natalia; Fidalgo Zorrilla, Jairo; Jalón Sotés, Félix Ángel; Manzano Manrique, Blanca Rosa; Carrión Núñez de Arenas, Mª del Carmen; Javier Torres Hernández.